© George Walker IV / Tennessean.com / USA TODAY NETWORK
The SF 49ers will host the Houston Texans who are off B2B upset wins over JAX and LAC last week where they won 41-29 as a 13 point dog but unfortunately for Houston teams off a SU upset win as a 13+ point dog are (12-26 ATS) over the years. The 49ers will be missing starting QB Jimmy G but even with a rookie backup and the line still being as high as it is tells you a lot. San Francisco is (22-7 ATS) off an upset road loss while the Texans are (0-6 ATS) off B2B wins over the L3 seasons. I expect SF to win this game by 2+ touchdowns.
Pick: SF 49ERS -13.5